This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.

Aliases：    R1; RR1; RIR1    

Entrez GeneID：    6240    

Swissprot：    P23921    

WB Predicted band size：    90kDa    

Host/Isotype：    Mouse IgG2a    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human RRM1 (AA: 541-792) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200-1/400    

ELISA    1/10000