This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Aliases: ARHE; Rho8; RhoE; memB
Entrez GeneID: 390
Swissprot: P61587
WB Predicted band size: 27.4kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human RND3 (AA: 104-241) expressed in E. Coli.