This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]

Aliases：    RIP; RIP1; IMD57; RIP-1    

Entrez GeneID：    8737    

Swissprot ：   Q13546    

WB Predicted band size ：   76kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human RIPK1 (AA: 131-277) expressed in E. Coli.    

WB    1/500 - 1/2000    

ELISA    1/10000