The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Aliases: CC1; ATG17; FIP200; PPP1R131
Entrez GeneID: 9821
Swissprot: Q8TDY2
WB Predicted band size: 183kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human RB1CC1 (AA: 148-244) expressed in E. Coli.