This gene encodes a Rabaptin, RAB GTPase Binding Effector Protein 2. The encoded protein Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking . By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis
Aliases: FRA
Entrez GeneID: 79874
Swissprot: Q9H5N1
WB Predicted band size: 63.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human RABEP2 (AA: 10-200) expressed in HEK293-6e cells supernatant.