This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Aliases： FIH1; PTH1
Entrez GeneID： 5741
Swissprot： P01270
WB Predicted band size： 12.8kDa
Host/Isotype： Mouse IgG2b
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human PTH (AA: 32-115) expressed in E. Coli.
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