PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Aliases: BLIMP1; PRDI-BF1; MGC118922; MGC118923; MGC118924; MGC118925; PRDM1
Entrez GeneID: 639
Swissprot: O75626
WB Predicted band size: 88kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse
Immunogen: Purified recombinant fragment of human PRDM1 expressed in E. Coli.