This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases：    DARPP32; DARPP-32    

Entrez GeneID：    84152    

Swissprot：    Q9UD71        

WB Predicted band size：    23kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000