The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Aliases：    PERC; ERRL1; PGC1B; PGC-1(beta)    

Entrez GeneID：    133522    

Swissprot ：   Q86YN6       

WB Predicted band size：    113.2kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000