This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
Aliases: BRN2; OCT7; OTF7; OTF-7; POUF3; brn-2; oct-7; N-Oct3
Entrez GeneID: 5454
Swissprot: P20265
WB Predicted band size: 46.9kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human POU3F2 (AA: 214-362) expressed in E. Coli.