This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Entrez GeneID： 5284
Swissprot： P01833
WB Predicted band size： 83.3kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunoge：n Purified recombinant fragment of human PIGR (AA: extra 19-170) expressed in E. Coli.
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