The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Aliases: PKH; PNK; HMSN6C; PRED79; C21orf97; HEL-S-1a; C21orf124
Entrez GeneID: 8566
Swissprot: O00764
WB Predicted band size: 35kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human, Mouse
Immunogen : Purified recombinant fragment of human PDXK (AA:1-312) expressed in E. Coli.