This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Aliases：    PDHK2; PDKII    

Entrez GeneID：    5164    

Swissprot ：   Q15119    

WB Predicted band size：    46.2kDa    

Host/Isotype ：   Mouse IgG2b    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human PDK2 (AA: 178-404) expressed in E. Coli.    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000