Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. (provided by RefSeq). Tissue specificity: Expressed predominantly in the heart.

Aliases：    PDK1    

Entrez GeneID ：   5163    

Swissprot ：   Q15118    

WB Predicted band size：    44kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Mouse,Rat,Monkey    

Immunogen ：   Purified recombinant fragment of human PDK1 expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000