This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.

Aliases:    PDGF1; PDGF-A    

Entrez GeneID:    5154    

Swissprot:    P04085    

WB Predicted band size:    24kDa    

Host/Isotype:    Mouse IgG2a    

Species Reactivity:    Human, Mouse    

Immunogen:    Purified recombinant fragment of human PDGFA (AA: 87-211) expressed in E. Coli.    

IF/ICC    1/50 - 1/200    

FCM    1/200 - 1/400    

ELISA    1/10000