The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Entrez GeneID: 5111
Swissprot : P12004
WB Predicted band size: 28.7kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse,Rat,Rabbit,Monkey
Immunogen: Purified recombinant fragment of human PCNA (AA: 53-196 ) expressed in E. Coli.
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