PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

Aliases：    PAK65; PAKgamma    

Entrez GeneID：    5062    

Swissprot：    Q13177      

WB Predicted band size：    61kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human,Monkey    

Immunogen ：   Purified recombinant fragment of PAK2 expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000