The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Aliases：    HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)    

Entrez GeneID：    64805    

Swissprot：    Q9H244    

WB Predicted band size ：  39.4kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human P2RY12 (AA: extra mix) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000