The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

Aliases ：   TNFRSF4; ACT35; CD134; IMD16; TXGP1L    

Entrez GeneID：    7293    

Swissprot ：   P43489    

WB Predicted band size：   29.3kDa    

Host/Isotype  ：  Mouse IgG2b    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human OX40 (AA: extra 29-214) expressed in HEK293 cells.    

FCM    1/200 - 1/400    

ELISA    1/10000