This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],

Aliases    NRP1;NRP;VEGF165R;Neuropilin-1;Vascular endothelial cell growth factor 165 receptor;CD antigen CD304    

Entrez GeneID：    8829    

Swissprot：    O14786    

WB Predicted band size：    103kD    

Host/Isotype：    Rabbit IgG,Kappa    

Species Reactivity ：   Human,Mouse,Rat,    

WB    1/1000-5000    

IP    1/50-200    

IHC    1/200-1000    

IF/ICC    1/200-1000    

ELISA    1/5000-20000