The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Aliases：    CAS2; CASL; HEF1; CAS-L; CASS2    

Entrez GeneID：    4739    

Swissprot ：   Q14511    

WB Predicted band size ：   92.9kDa    

Host/Isotype：   Mouse IgG1    

Species Reactivity：    Human, Rat    

Immunogen ：   Purified recombinant fragment of human NEDD9 (AA: 82-398) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000