N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants.

Aliases:    TE2; ARD1; NATD; ARD1A; ARD1P; OGDNS; DXS707; MCOPS1    

Entrez GeneID:    8260    

Swissprot:    P41227    

WB Predicted band size:    26.5kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity:    Human,Mouse,Monkey    

Immunogen :   Purified recombinant fragment of human NAA10 (AA: 111-235) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000