This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

Aliases:    PUM; MYF3; MYOD; bHLHc1; MYODRIF    

Entrez GeneID:    4654    

Swissprot:   P15172    

WB Predicted band size:    34.5kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human    

Immunogen:    Purified recombinant fragment of human MYOD1 (AA: 221-320) expressed in E. Coli.    

IF/ICC    1/50 - 1/200    

FCM    1/200 - 1/400    

ELISA    1/10000