This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases:    NMYC; ODED; MODED; N-myc; bHLHe37    

Entrez GeneID:    4613    

Swissprot:    P04198        

WB Predicted band size:    49.5kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human    

Immunogen :   Purified recombinant fragment of human MYCN (AA: 337-464) expressed in E. Coli.    

IHC    1/200-1/1000    

FCM    1/200-1/400    

ELISA    1/10000