This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.

Aliases:    MG1; MUC5; MUC9; MUC-5B    

Entrez GeneID:    727897    

Swissprot:    Q9HC84    

WB Predicted band size:   596kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity:    Human    

Immunogen:   Purified recombinant fragment of human MUC5B (AA: 26-166) expressed in E. Coli.    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000