The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Aliases: FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Entrez GeneID: 2475
Swissprot: P42345
WB Predicted band size: 289kDa
Host/Isotype: Mouse IgG2a
Species Reactivity: Human,Mouse,Rat,Rabbit
Immunogen: Purified recombinant fragment of human mTOR (AA: 2311-2529) expressed in E. Coli.
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