The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Aliases： MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
Entrez GeneID： 8714
Swissprot ： O15438
WB Predicted band size ： 43kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human, Mouse, Rat
Immunogen ： Purified recombinant fragment of human MRP3 (AA: 830-949) expressed in E. Coli.
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