The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.
Aliases : MOB1; MATS1; Mob4B; C2orf6; MOBK1B; MOBKL1B
Entrez GeneID: 55233
Swissprot: Q9H8S9
WB Predicted band size: 25kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human MOB1A (AA:1-216) expressed in E. Coli.