This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Aliases:    MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14    

Entrez GeneID:    51085    

Swissprot:    Q9NP71    

WB Predicted band size:    93.1kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity:    Human    

Immunogen :   Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000