This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Aliases:    MER; RP38; c-Eyk; c-mer; Tyro12    

Entrez GeneID:    10461    

Swissprot :   Q12866    

WB Predicted band size :   140-180 kDa    

Host/Isotype:    Mouse IgG2b    

Species Reactivity:    Human,Mouse    

Immunogen:    Purified recombinant fragment of human MERTK (AA:extra(21-220)) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000