This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

Aliases：    MAT; SAMS; MATA1; SAMS1; MAT1A    

Entrez GeneID：    4146    

Swissprot ：   P21941    

WB Predicted band size ：   54kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human MATN1 expressed in E. Coli.    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000