The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Aliases ：   MEKK2; MEKK2B    

Entrez GeneID：    10746    

Swissprot ：   Q9Y2U5    

WB Predicted band size ：   70kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human    

Immunogen  ：  Purified recombinant fragment of human MAP3K2 expressed in E. Coli.    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000