This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

Aliases ：   HS; NIK; HSNIK; FTDCR1B    

Entrez GeneID：    9020    

Swissprot：   Q99558    

WB Predicted band size ：   104kDa    

Host/Isotype  ：  Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human MAP3K14 (AA: 769-947) expressed in E. Coli.    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000