This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

Aliases ：   PARK8; RIPK7; ROCO2; AURA17; DARDARIN    

Entrez GeneID：   120892    

Swissprot  ：  Q5S007       

WB Predicted band size：    286kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human LRRK2 (AA: 300-530) expressed in E. Coli.    

IF/ICC    1/50 - 1/200    

FCM    1/200 - 1/400    

ELISA    1/10000