LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Aliases:    TTG2; RBTN2; RHOM2; RBTNL1    

Entrez GeneID :   4005    

Swissprot:    P25791    

WB Predicted band size:    18.4kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity:    Human    

Immunogen    Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000