LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.

Aliases:    CSDD1; LIN-28; LIN28A; ZCCHC1    

Entrez GeneID :   79727    

Swissprot:    Q9H9Z2    

WB Predicted band size :   23kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity :   Human    

Immunogen  :  Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000