This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Aliases: K14; NFJ; CK14; EBS1; EBS3; EBS4; EBS1A; EBS1B; EBS1C; EBS1D
Entrez GeneID: 3861
Swissprot: P02533
WB Predicted band size: 51.5kDa
Host/Isotype : Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human KRT14 (AA: 115-472) expressed in E. Coli.