The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Aliases：    ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114    

Entrez GeneID：    8085    

Swissprot ：   O14686    

WB Predicted band size：    593kDa    

Host/Isotype：    Mouse IgG2b    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000