This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]
Aliases : HALR; MLL3; KLEFS2
Entrez GeneID: 58508
Swissprot: Q8NEZ4
WB Predicted band size: 541.4kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen : Purified recombinant fragment of human KMT2C (AA: 1-205) expressed in E. Coli.