This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Aliases : JMJD2; JHDM3A; JMJD2A; KIAA0677; KDM4A
Entrez GeneID : 9682
Swissprot: O75164
WB Predicted band size : 120kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human KDM4A expressed in E. Coli.