The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Aliases：    IK; IK1; SK4; DHS2; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1    

Entrez GeneID：    3783    

Swissprot ：   O15554     

WB Predicted band size：    47.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human KCNN4 (AA: extra 286-427) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/50 - 1/200    

FCM    1/200 - 1/400    

ELISA    1/10000