This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Aliases ：   JMJ    

Entrez GeneID：    3720    

Swissprot ：   Q92833      

WB Predicted band size：    139kDa    

Host/Isotype：    Mouse IgG2a    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human JARID2 (AA: 1097-1246) expressed in E. Coli.    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000