Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.Tissue specificity: Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

Aliases：    IL-34; C16orf77; MGC34647; IL34    

Entrez GeneID：    146433    

Swissprot ：   Q6ZMJ4    

WB Predicted band size：    27.5kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human IL34 expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000