The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Aliases：    IL-1; IL1F2; IL1-BETA    

Entrez GeneID：    3553    

Swissprot ：   P01584    

WB Predicted band size：    31kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human IL1B expressed in E. Coli.    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000