Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease
Aliases IL1; IL-1A; IL1F1; IL1-ALPHA
Entrez GeneID： 3552
Swissprot： P01583
WB Predicted band size ： 30.6kDa
Host/Isotype： Mouse IgG2a
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human IL1a expressed in E. Coli.
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