The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Aliases：    KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3    

Entrez GeneID：    10643    

Swissprot：    O00425      

WB Predicted band size：    63.7kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human IGF2BP3 (AA: 430-579) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200-1/1000    

FCM    1/200-1/400    

ELISA    1/10000