This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Aliases: CD119; IFNGR; IMD27A; IMD27B
Entrez GeneID: 3459
Swissprot: P15260
WB Predicted band size: 54.4kDa
Host/Isotype: Mouse IgG2b
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human IFNGR1 (AA: extra 18-245) expressed in HEK293-6e cells supernatant.