This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Aliases: IFG; IFI
Entrez GeneID: 3458
Swissprot: P01579
WB Predicted band size: 19.3kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen : Purified recombinant fragment of human IFN-γ expressed in E. Coli.