The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
Aliases : AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
Entrez GeneID: 3454
Swissprot : P17181
WB Predicted band size : 63.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human, Mouse
Immunogen: Purified recombinant fragment of human IFNAR1 (AA: 28-156) expressed in E. Coli.