Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Aliases ： CTM
Entrez GeneID： 3299
Swissprot ： Q9ULV5
WB Predicted band size： 53kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human HSF4 expressed in E. Coli.
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